Mapping Polycomb Response Elements at the Drosophila melanogaster giant Locus
نویسندگان
چکیده
منابع مشابه
Mapping Polycomb Response Elements at the Drosophila melanogaster giant Locus
Polycomb-group (PcG) proteins are highly conserved epigenetic transcriptional regulators. They are capable of either maintaining the transcriptional silence of target genes through many cell cycles or enabling a dynamic regulation of gene expression in stem cells. In Drosophila melanogaster, recruitment of PcG proteins to targets requires the presence of at least one polycomb response element (...
متن کاملP-Element Homing Is Facilitated by engrailed Polycomb-Group Response Elements in Drosophila melanogaster
P-element vectors are commonly used to make transgenic Drosophila and generally insert in the genome in a nonselective manner. However, when specific fragments of regulatory DNA from a few Drosophila genes are incorporated into P-transposons, they cause the vectors to be inserted near the gene from which the DNA fragment was derived. This is called P-element homing. We mapped the minimal DNA fr...
متن کاملMolecular mapping of the rosy locus in Drosophila melanogaster.
The DNA from the chromosomal region of the Drosophila rosy locus has been examined in 83 rosy mutant strains. Several spontaneous and radiation-induced alleles were associated with insertions and deletions, respectively. The lesions are clustered in a 4-kb region. Some of the alleles identified on the DNA map have been located on the genetic map by fine-structure recombination experiments. The ...
متن کاملEvolutionary Plasticity of Polycomb/Trithorax Response Elements in Drosophila Species
cis-Regulatory DNA elements contain multiple binding sites for activators and repressors of transcription. Among these elements are enhancers, which establish gene expression states, and Polycomb/Trithorax response elements (PREs), which take over from enhancers and maintain transcription states of several hundred developmentally important genes. PREs are essential to the correct identities of ...
متن کاملLocus of Drosophila Melanogaster
I N a previous paper (LIFSCHYTZ and FALK 1969b) we showed that by using the specific interaction pn-K-pn (prune--Killer-prune) we could construct an efficient screening system in which the products of reversions in the p n and K-pn loci were the only viable male-progeny. The few female progeny that survived served for estimating the number of tested zygotes. K p n is a dominant mutant, interact...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: G3 Genes|Genomes|Genetics
سال: 2013
ISSN: 2160-1836
DOI: 10.1534/g3.113.008896